2012
IWISH 2012 Proceeding
Modular modelling and hybrid combination in health technology assessment models ? examples and technology
Authors: Günther Zauner, Patrick Einzinger, Florian Miksch, I. Zechmeister, Gottfried Endel, Felix Breitenecker
Abstract
Simulation of communicable diseases is an important field of interest in HTA. As requirements of stakeholders in the field of HTA are getting higher there is a need for complex models using different approaches. A concept to deal with the increasing effort and complexity is to split up models into single parts, so called modules, which enables easier development, more flexibility and reusability. In this work we concentrate on two different modular approaches for simulation of epidemics The agent based approach, dealing with individual behavior of persons. A model for Influenza with different environments, a model for Streptococcus- Pneumoniae with complex infection rules and another influenza-model with social interaction deal as examples. The top-down approach starts with the epidemiological part where, epidemiological outcomes are calculated in a more general way, following by the demographical part. It ends with the economical part that calculates costs and evaluates economic aspects. A model for human papillomavirus vaccination (HPV) serves as an example.
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