IWISH 2012 Proceeding

Modeling the effects of intra-abdominal hypertension

Authors:   Jerry Batzel, Stefan Fürtinger, Daniel Schneditz

Abstract

Intra-abdominal hypertension denotes elevated pressure in the abdomen. Such hypertension is common in patients in critical care hospital wards. The consequences of intra-abdominal hypertension involve constrained blood flow to vital organs such as the kidneys and abdominal organs (in connection with reduced cardiac output) potentially leading to multi- organ failure) Intra-abdominal hypertension represents an independent risk factor for mortality in acute and intensive care patients. Even given these observations, this condition is not always adequately monitored and much remains to be learned about its evolution and its impact on cardiovascular function. In addition, no significant modeling studies or models have been proposed to study this phenomenon. In this paper, we will discuss this problem, relevant mechanisms, and a model to simulate the effects of intra-abdominal hypertension on the cardiovascular system.

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