Authors: Vera Gramigna, Maria Vittoria Caruso, Attilio Renzulli, Gionata Fragomeni
The experience of combining extra-corporeal membrane oxygenation (ECMO) with intra-aortic balloon pump (IABP) for the treatment of acute heart failure in critically ill adults can in principle have a synergistic and complementary effect. ECMO is a medical procedure used to supply oxygen to the blood circulation of patient with cardiac/ pulmonary failure. Since linear flow in ECMO is often responsible for some clinical problems, aim of this study was to evaluate the hemodynamic difference in the aorta due to linear and pulsed ECMO, the latter obtained with the IABP, currently the most commonly used mechanical circulatory support device. A multiscale model, realized coupling a 3D CFD analysis with a lumped parameters model (resistance's boundary conditions), was carried out. The numerical results showed that the aortic flow followed the balloon radius behavior's change. Therefore pulsatility similar to the arterial one, in respect of the linear standard behaviour (IABP not inserted), occurred.